Advanced Search

The Journal of Neuropsychiatry and Clinical Neurosciences, VOL. 1, No. 2

Article | May 01, 1989

White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly

The Journal of Neuropsychiatry and Clinical Neurosciences 1989;1:135-144.

Article

text A A A

PDF of the full text article.

Abstract

In a prospective study of depressed elderly patients referred for electroconvulsive therapy (ECT), subcortical white matter hyperintensity (WMH) was seen in all 51 patients 60 years or older who received magnetic resonance imaging (MRI) prior to treatment. In over half of the patients the WMH was formally rated as at least moderately severe, and it was commonly associated with other structural brain changes. The majority (80%) of patients had late-age-onset depression, suggesting that structural brain changes may interact with aging to facilitate the emergency of depression in late life.

Figures in this Article

Your Session has timed out. Please sign back in to continue.

Username

Password

Sign in via Athens (What is this?)

Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.

Forgot Password?

Not a subscriber?

Subscribe Now/Learn More

Purchase Online access to this article for 24 hours

PsychiatryOnline subscription options offer access to the DSM-IV-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.

Submit a Comments

Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of JBJS editorial staff.

* = Required Field

Comment Author(s)*(if multiple authors, separate names by comma)

Example: John Doe

Affiliation & Institution*

Comment Title*

Comment*

Cancel

Topics

Product Recommendation

CME Activity