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The Journal of Neuropsychiatry and Clinical Neurosciences, VOL. 2, No. 4

Article | November 01, 1990

Dexamethasone suppression test and depressive symptoms in bereaved children: a preliminary report

The Journal of Neuropsychiatry and Clinical Neurosciences 1990;2:418-421.

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Abstract

Eighteen bereaved children and adolescents were assessed using the dexamethasone suppression test (DST) and the Diagnostic Interview for Children and Adolescents 4 weeks following parental death. Thirty-nine percent had a positive (nonsuppressed) DST. DST-positive subjects reported more DSM-III-R depressive symptoms (6.3 +/- 2.9 vs. 3.9 +/- 2.7, means +/- SD) than DST-negative subjects. Most frequently reported symptoms included dysphoria, loss of interest, sleep disturbance, appetite disturbance, psychomotor disturbance, and morbid and suicidal ideation. Post-dexamethasone cortisol levels were significantly correlated with the total number of depressive symptoms and suicidal ideation.

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