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The Journal of Neuropsychiatry and Clinical Neurosciences, VOL. 3, No. 4

Article | November 01, 1991

Visual evoked potentials in dementia: selective delay of flash P2 in probable Alzheimer's disease

The Journal of Neuropsychiatry and Clinical Neurosciences 1991;3:431-435.

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Abstract

The flash visual evoked potential P2 component is delayed in etiologically mixed groups of demented patients compared to healthy controls or nondemented patients. This study compared patients meeting both DSM-III-R criteria for dementia and NINCDS-ADRDA criteria for probable Alzheimer's disease (AD) with healthy elderly controls and found the P2 delay in the probable AD group. Additional comparisons found no evidence of a P2 delay in demented unlikely AD patients. These results suggest that earlier findings of a delayed P2 in etiologically mixed demented groups may have been due to inclusion of AD patients.

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