The cognitive and motor deficits associated with human immunodeficiency
virus-1 (HIV-1) infection have been studied using neurological examination
and neuropsychological tests. However, drug users with HIV- 1 infection
generally have been excluded from such studies. Forty-four
well-characterized drug users stratified by Centers for Disease Control
staging were administered a standardized neurological examination and a
battery of neuropsychological tests under single-blind conditions designed
to minimize the acute effects of psychoactive substances. The results of
the blind neurological examination were consistent with the previously
ascertained clinical staging of HIV-1 infection. The pattern of
neuropsychological deficits across HIV-1 states was similar to those found
in cohorts of homosexual men.Abstract Teaser