Antiphospholipid antibodies, including lupus anticoagulant and
anticardiolipin antibodies, are increasingly recognized as a cause of
neurological morbidity. They may occur with or without evidence of systemic
lupus erythematosus and have been associated with stroke, migraine, and
confusional states. Their role as etiologic or contributing factors in
neurobehavioral and neuropsychiatric syndromes of obscure etiology has not
been emphasized. The cases of 7 patients who were referred for evaluation
of behavior abnormalities and had antiphospholipid antibodies are
presented, and the potential relationships of the antiphospholipid antibody
syndrome to behavioral alterations are discussed.Abstract Teaser