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The Journal of Neuropsychiatry and Clinical Neurosciences, VOL. 7, No. 4

Article | November 01, 1995

Successful methylphenidate treatment of apathy after subcortical infarcts

The Journal of Neuropsychiatry and Clinical Neurosciences 1995;7:502-504.

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Abstract

A patient with prominent apathy secondary to multiple subcortical infarcts was treated successfully with methylphenidate. SPECT and reaction time testing showed selective improvement of frontal system function, consistent with a recent model of frontal-subcortical circuits and behavior.

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