The authors examined the presence of specific quantified
electroencephalographic (qEEG) changes in dementia patients with relatively
lower frontal or parietal blood perfusion as demonstrated by SPECT. Over
all brain regions, patients with relatively lower parietal perfusion showed
significantly higher theta relative power than demented patients with
relatively lower frontal perfusion or normal control subjects. Dementia
patients with relatively lower frontal perfusion showed no differences from
age-comparable normal control subjects in qEEG variables. These findings 1)
suggest that usefulness of qEEG for the diagnosis of dementia is restricted
to a subgroup of patients with the typical SPECT pattern of parietal blood
hypoperfusion and 2) demonstrate that the qEEG changes typical of dementia
are not related to perfusion deficits in frontal brain areas.Abstract Teaser