Cognitive and mood changes are central components of solvent
encephalopathy. This study examined event-related potentials in relation to
neuropsychological and psychiatric function in solvent- exposed adults.
Results revealed that longer P300 latency was associated with poorer
cognitive test scores, whereas reduced P300 amplitude was related to
increased psychiatric symptomatology. The findings suggest that the
cognitive deficits and the psychiatric disturbance following solvent
exposure may have different neurophysiological bases.Abstract Teaser