Neuropsychiatric symptoms are common manifestations of temporolimbic
lesions. These neuropsychiatric symptoms result from disturbances of
specific temporolimbic networks, including medial limbic circuits, lateral
limbic circuits, and the "extended" amygdala. Moreover, temporolimbic
networks interface with multiple cortical and subcortical circuits that
modulate emotional behavior and affect. This article not only reviews these
behaviorally relevant aspects of temporolimbic neuroanatomy, but also
describes positive, productive symptoms from the temporal lobes. The
Kluver-Bucy syndrome, the Gastaut-Geschwind syndrome, emotional or mood
disorders, delusions, anxiety and associative disorders, and
neurovegetative symptoms are discussed, as well as amnesia, the signature
temporolimbic disturbance of cognition. The temporolimbic lobe is a classic
example of a widely distributed circuit within the brain that has
behaviorally relevant manifestations.Abstract Teaser