GABA-ergic neurotransmission is important in shaping plastic responses of the CNS to somatosensory and other stimuli, including the maintenance and plasticity of cortical receptive fields. GABA, along with dopamine, is, therefore,a neurotransmitter most plausibly linked to the electrophysiological mechanisms identified in dystonia.1 Most of the work related to the role of GABA in this condition is reported with primary dystonia. A decreased GABA level selectively in cortical and subcortical regions contralateral to the dystonic limb in task-induced dystonia has been reported. Levy and Hallett2 speculated that deficient GABA levels could be consistent with reduced dopaminergic neurotransmission in the putamen, since D2 dopamine receptors mostly inhibit the GABA-ergic striatal medium spiny neurons. Drugs that potentiate GABA neurotransmission, such as baclofen, are effective against dystonic movements.3 Moreover, application of the GABA antagonist bicuculline to the motor cortex of monkeys causes abnormal co-contraction of agonist and antagonist muscle groups during activities requiring fine motor skills, and produces abnormal movements reminiscent of task-specific dystonia.4 Alcohol withdrawal is a state characterized by an imbalance of GABA-ergic and glutaminergic systems in the brain. Long-term alcohol consumption affects brain receptors, which undergo adaptive changes in an attempt to maintain normal function. Withdrawal state involves reduced brain GABA levels and GABA-receptor sensitivity and activation of glutamate systems, which leads to nervous system hyperactivity in the absence of alcohol.5 Benzodiazepines are an established treatment modality for alcohol withdrawal,6 and, similarly, baclofen has been effectively used both in the treatment of alcohol-withdrawal and dystonia.7 Dystonia can be conceptualized as an epiphenomenon of alcohol withdrawal, as given in this report, due to this shared neurochemical abnormality. To our knowledge, this is the first report of dystonia as a presenting feature of the alcohol-withdrawal state.