In August 2010, the patient presented at our psychiatric clinic. There had been no relevant changes in comorbid medical conditions and medication in the last 5 years, with the exception of the discontinuation of glucocorticoid therapy. The patient described that, during prednisone withdrawal, she had experienced nausea, myalgia, arthralgia, and headache. We saw an 85-year-old woman in good general condition. Neurological examination revealed tonic pupils, with missing light reaction and areflexia. During the psychopathological examination, the patient showed moderately depressed mood, anhedonia, and reported difficulties in falling asleep. The hyperhidrosis attacks had qualitatively changed since 2006, and now occurred spontaneously without identifiable trigger situations and a frequency of up to three times daily. They were accompanied by holocephalic pressure, a feeling like “a tempest in the brain,” tachycardia, prickling or numbness of hands and feet, nausea, the inability to speak, and the fear of “becoming crazy.” The patient also had developed marked anxiety concerning the next attack. These symptoms fulfilled diagnostic criteria for panic disorder without agoraphobia. The patient received psychopharmacological treatment with citalopram up to 60 mg/day and cognitive-behavioral therapy. Within the course of 6 weeks, the frequency and severity of panic attacks was notably reduced, and the patient returned to euthymic mood.