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Introducing a New Method for Early Diagnosis of Parkinson’s Disease
Yashar Sarbaz; Shahriar Gharibzadeh, M.D., Ph.D.; Akbar Soltanzadeh; Farzad Towhidkhah; Masood Banaie
The Journal of Neuropsychiatry and Clinical Neurosciences 2012;24:10010-10010. 10.1176/appi.neuropsych.11080190
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Amirkabir University of Technology Tehran, Islamic Republic of Iran

Amirkabir University of Technology - Biomedical Engineering Tehran, Islamic Republic of Iran

University of Tehran Tehran, Islamic Republic of Iran

Amirkabir University of Technology - Biomedical Engineering Tehran, Islamic Republic of Iran

Shahed University - Biomedical Engineering Tehran, Islamic Republic of Iran

Extract

To the Editor: Parkinson’s disease (PD) is a common neurological disorder without absolute treatment. The patients would need to ask a physician for a treatment usually after 50 to 80% destruction in Substantia Nigra pars compacta (SNc).1 Therefore, the process of SNc destruction is started several years before the diagnosis of PD by the physician. Diagnosis time plays a key role in controlling the PD and postponing the disabling stages of the disease. Therefore, the disease should be diagnosed as soon as possible. Since the disease has definite motor symptoms, it seems that considering these symptoms may help to separate the at risk persons. One of the most important motor symptoms is gait disorder which is the result of rigidity, bradykinesia, postural imbalance, etc. Therefore, it seems that designating a simple walking test in general check-up tests may be helpful in early diagnosis of PD.

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References

Kandel  ER;  Schwartz  JH;  Jessell  TM:  Principles of Neural Science , 4th ed.  New York,  McGraw-Hill,  2000
 
Hausdorff  JM;  Cudkowicz  ME;  Firtion  R  et al.:  Gait variability and basal ganglia disorders: stride-to-stride variations of gait cycle timing in Parkinson’s disease and Huntington’s disease.  Mov Disord   1998; 13:428–43710.1002/mds.870130310
[PubMed]
[CrossRef]
 
Okuno  R;  Fujimoto  S;  Akazawa  J  et al.: Analysis of spatial temporal plantar pressure pattern during gait in Parkinson’s disease. 30th Annual International IEEE EMBS Conference Vancouver, British Columbia, Canada, August 20-24.  2008.
 
Factor  SA;  Weiner  WJ:  Parkinson’s disease Diagnosis and Clinical Management , 2nd ed.  New York,  Demos Medical Publishing,  2008
 
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