A 20-year-old Taiwanese man was admitted for psychiatric inpatient treatment because of schizophrenia. The patient presented the symptoms of incoherent speech, disorganized behavior, and delusions of reference. He denied history of drug abuse or cardiovascular disease. Initial laboratory studies revealed normal ranges, with blood pressure of 120/70 mm Hg and heart rate of 60 bpm. An initial electrocardiogram(ECG) revealed normal sinus rhythm. He was treated with aripiprazole 15 mg per day, but he complained of dizziness and weakness, with blood pressure of 65/33 mmHg after aripiprazole 15 mg. Supportive treatment with oxygen were prescribed immediately; the patient felt better 6 hours later, except for dizziness. After this episode, aripiprazole was tapered down to 5 mg per night in the following days. Indeed, his blood pressure returned to a normal range, and he complained of no further symptoms, such as dizziness or chest discomfort, during the following days and nights.