To the Editor: A 5-year-old boy of Chinese descent presented to the Early Emotional Development Program at Washington University with a history of bilateral amygdala loss of unknown etiology. His adoptive parents reported that he had been adopted at the age of 18 months from an institutional setting; several months after his adoption, he began to eat less, and, by the age of 22 months, he refused all food. During the first year in his adoptive home, he became aggressive, displaying spontaneous aggression toward his adoptive family. His adoptive parents also described him as being “fearless,” unafraid of strangers or situations that could, and did, cause him harm. We report our clinical observations and the results of testing of this unique child and discuss implications for early brain neuroplasticity.