According to the above-mentioned notes, we believe that, in MS, wrong detection of non-self-cells reflects the poor functioning of the innate immune system in memory formation of the adaptive system. Although current therapeutic researches are focusing on changes in the concentration of T-cells that secrete cytokine, we believe that the whole immune system may be considered as a connected network, in which the concentrations of secreted cytokines are more important than T-cell concentration. Based on this idea, changes in chemical conditions around the cells would dynamically alter the network structure by changing the internal interactions, that is, cytokine secretions. From this point of view, the immune system acts in a self-organized manner, in which internal positive and negative feedbacks give more adaptation ability to this network. Applying this idea would be promising to find novel treatment techniques. However, more experimental data and modeling studies are required to indicate whether our suggestion is plausible.