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Clinical and Research Reports   |    
Aggression, Impulsivity, and Psychopathic Traits in Combined Antisocial Personality Disorder and Substance Use Disorder
Joseph L. Alcorn, III, B.S.; Joshua L. Gowin, Ph.D.; Charles E. Green, Ph.D.; Alan C. Swann, M.D.; F. Gerard Moeller, M.D.; Scott D. Lane, Ph.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:229-232. doi:10.1176/appi.neuropsych.12030060
View Author and Article Information

This work was funded by NIH grants DA R01 003166 and DA P50 09262.

From the Dept. of Psychiatry & Behavioral Sciences, School of Medicine, the Program in Neuroscience, Graduate School of Biomedical Sciences, and the Center for Clinical Research & Evidence-Based Medicine, University of Texas Health Science Center, Houston, TX.

Send correspondence to Dr. Alcorn or Dr. Scott; e-mail: Joseph.Alcorn@uth.tmc.edu or scott.d.lane@uth.tmc.edu

Copyright © 2013 American Psychiatric Association

Received March 15, 2012; Revised November 05, 2012; Accepted January 04, 2013.

Abstract

Aggression, impulsivity, and psychopathic traits are prominent in both antisocial personality disorder (ASPD) and substance use disorders (SUD), but have rarely been examined collectively. The authors’ results show that all three variables were elevated in adults with comorbid ASPD/SUD, relative to SUD-only and control subjects.

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TABLE 1.Summary of Demographic and Dependent Measures in Each Group
Table Footer Note

Values are mean (standard deviation). There were no statistically significant between-group differences in age, education, or Shipley–2 score. Years of use: the average number of years in which subjects used a drug for which SUD criteria were met; ASPD: antisocial personality disorder; SUD: substance use disorder.

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a Shipley–2: Shipley Institute of Living Scale–2: Vocabulary+Block Forms Composite Score (Shipley et al., 2009, Western Psychological Services, CA)

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PSAP: Point Subtraction Aggression Paradigm; PM-IPAS: Impulsive Premeditated Aggression Scale–Premeditated Subscale; IA-IPAS: Impulsive Premeditated Aggression Scale–Impulsive Subscale; BPAQ: Buss-Perry Aggression Questionnaire; BIS–II: Barratt Impulsiveness Scale–II; SRP-III: Self Report of Psychopathy Scale–III.

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TABLE 2.Results of One-Way ANOVA Conducted Among Groups on All Six Dependent Measures
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a: ASPD+SUD > Control; b: ASPD+SUD > SUD-only; c: SUD > Control.

Table Footer Note

PSAP: Point Subtraction Aggression Paradigm; PM-IPAS: Impulsive Premeditated Aggression Scale–Premeditated Subscale; IA-IPAS: Impulsive Premeditated Aggression Scale–Impulsive Subscale; BPAQ: Buss-Perry Aggression Questionnaire; BIS–II: Barratt Impulsiveness Scale–II; SRP-III: Self Report of Psychopathy Scale–III.

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