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Treatment of Catatonia With Zolpidem
Stephanie Peglow, D.O.; Vladimir Prem, M.D.; William McDaniel, M.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:E13-E13. doi:10.1176/appi.neuropsych.11120367
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Dept. of Psychiatry Eastern Virginia Medical School Norfolk, VA
Veterans Affairs Medical Center Norfolk, VA

Correspondence: Stephanie Peglow, D.O.; peglowsl@evms.edu

Copyright © 2013 American Psychiatric Association


To the Editor: Zolpidem has been used successfully as a rapid test for patients suspected to be catatonic.1 Lorazepam or electroconvulsive therapy (ECT) are considered the standard of care.2 Zolpidem is well-described as a test for catatonia.3 This case report explores zolpidem as a long-term treatment option when standard therapies are not tolerated or ineffective.

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catatonia ; zolpidem
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Thomas  P;  Cottencin  O;  Rascle  C  et al:  Catatonia in French psychiatry: implications of the Zolpidem Challenge Test.  Psychiatr Ann 2007; 37:45–54
Bush  G;  Fink  M;  Petrides  G  et al:  Catatonia, II: treatment with lorazepam and electroconvulsive therapy.  Acta Psychiatr Scand 1996; 93:137–143
[CrossRef] | [PubMed]
Mastain  B;  Vaiva  G;  Guerouaou  D  et al:  [Favorable effect of zolpidem on catatonia].  Rev Neurol (Paris) 1995; 151:52–56
Tu  JB;  Bistow  M:  Neuroleptic malignant syndrome: a psychopharmacogenetic perspective.  J Child Adolesc Psychopharmacol 1996; 6:151–152
[CrossRef] | [PubMed]
Ungvari  G;  Kau  L;  Wal-Kwong  T;  Shing  N: The pharmacological treatment of catatonia: an overview. Eur Arch Psychiatry Clin Neurol 2001; 251:31–34
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