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Letters   |    
Othello Syndrome in a Patient With Right Orbitofrontal Lobe Cavernous Sinus Hemorrhage
Chiu-Ping Hsiao, M.D.; Nian-Sheng Tzeng, M.D.; Chun-Jung Juan, M.D., Ph.D.; Shin-I Ma, M.D., Ph.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:E14-E15. doi:10.1176/appi.neuropsych.11120370
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No financial support was received for this report.

Dept. of Psychiatry (C-PH, N-ST) Dept. of Radiology (C-JJ) Dept. of Neurosurgery (S-IM) Tri-Service General Hospital School of Medicine Student Counseling Center (N-ST) National Defense Medical Center (C-PH, N-ST, C-JJ, S-IM) Taipei, Taiwan

Correspondence: Nian-Sheng Tzeng, M.D.; e-mail: hcpyvonne@yahoo.com.tw; pierrens@yahoo.com.tw

Copyright © 2013 American Psychiatric Association

Extract

To the Editor: Othello syndrome (OS), with delusions of spousal infidelity, is related to a variety of etiologies, such as delusional disorder, schizophrenia, dementia, and other organic mental disorders. Here, we report a patient with cortical atrophy and cavernous sinus hemorrhage, whose Othello syndrome was subsequently treated.

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FIGURE 1. MRI Study of 85-Year-Old With Othello Syndrome

[A]: Old hemorrhage from cavernous sinus on proximal right orbitofrontal gyrus; [B]: single prominent venous drainage and collecting cortical veins; [C]: right cavernous sinus and branches of this venous anomaly cover the neighboring tissue near the old hemorrhage site.

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References

Richardson  ED;  Malloy  PF;  Grace  J:  Othello syndrome secondary to right cerebrovascular infarction.  J Geriatr Psychiatry Neurol 1991; 4:160–165
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Georgiev  D;  Danieli  A;  Ocepek  L  et al:  Othello syndrome in patients with Parkinson’s disease.  Psychiatr Danub 2010; 22:94–98
[PubMed]
 
Westlake  RJ;  Weeks  SM:  Pathological jealousy appearing after cerebrovascular infarction in a 25-year-old woman.  Aust N Z J Psychiatry 1999; 33:105–107
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Malloy  PF;  Richardson  ED:  The frontal lobes and content-specific delusions.  J Neuropsychiatry Clin Neurosci 1994; 6:455–466
[PubMed]
 
Sultzer  DL;  Brown  CV;  Mandelkern  MA  et al:  Delusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer’s disease.  Am J Psychiatry 2003; 160:341–349
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Bisol  LW;  Lara  DR:  Low-dose risperidone for pathological jealousy: report of three cases.  J Clin Psychopharmacol 2008; 28:595–596
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