0
Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

Letters   |    
A Case of Schizophrenia Accompanied By Lissencephaly
Akiko Kawaguchi, M.D.; Shutaro Nakaaki, M.D., Ph.D.; Takatsune Kawaguchi, M.D., Ph.D.; Tatsuo Akechi, M.D., Ph.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:E17-E18. doi:10.1176/appi.neuropsych.12090215
View Author and Article Information

Dept. of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences (AK, TA)
Laboratory of Aging, Behavior, and Cognition, Dept. of Neuropsychiatry, Keio University School of Medicine (SN)
Dept. of Radiology, Nagoya City University Graduate School of Medical Sciences (TK)

Correspondence: Akiko Kawaguchi, M.D.; e-mail: ig301043@yahoo.co.jp

Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan

Copyright © 2013 by the American Psychiatric Association

Extract

To The Editor: Lissencephaly is one of the cortical dysplasia diseases that include schisencephaly, polymicrogria, and heterotopic gray matter. These diseases are caused by defective neuronal migration. Cortical dysplasia is often accompanied by severe mental retardation and intractable epilepsy; however, there are very few reported cases of cortical dysplasia with psychotic symptoms,1,2 and, before the present case, we found no reports on lissencephaly with psychotic symptoms. Here, we experienced a case of schizophrenia accompanied by lissencephaly with cerebellar hypoplasia.

Figures in this Article

First Page Preview

View Large
/>
First page PDF preview
Your Session has timed out. Please sign back in to continue.
Sign In Your Session has timed out. Please sign back in to continue.
Sign In to Access Full Content
 
Username
Password
Sign in via Athens (What is this?)
Athens is a service for single sign-on which enables access to all of an institution's subscriptions on- or off-site.
Not a subscriber?

Subscribe Now/Learn More

PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing PsychiatryOnline@psych.org or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

FIGURE 1. Mild Lissencephaly, Dominant in the Temporal and Occipital Lobes, Mild Atrophy of the Right Hippocampus, and Hypoplasia of the Cerebellum
+

References

Alexander  RC;  Patkar  AA;  Lapointe  JS  et al:  Schizencephaly associated with psychosis.  J Neurol Neurosurg Psychiatry 1997; 63:373–375
[CrossRef] | [PubMed]
 
Komori  K;  Komori  M;  Hayashi  J:  [A cases of schizencephaly associated psychosis].  No To Shinkei 2006; 58:611–614
[PubMed]
 
Guidotti  A;  Auta  J;  Davis  JM  et al:  Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study.  Arch Gen Psychiatry 2000; 57:1061–1069
[CrossRef] | [PubMed]
 
Liu  WS;  Pesold  C;  Rodriguez  MA  et al:  Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse.  Proc Natl Acad Sci USA 2001; 98:3477–3482
[CrossRef] | [PubMed]
 
References Container
+
+

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe



Related Content
Books
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 46.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 46.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 46.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 46.  >
The American Psychiatric Publishing Textbook of Psychopharmacology, 4th Edition > Chapter 46.  >
Topic Collections
Psychiatric News
Read more at Psychiatric News >>
APA Guidelines
PubMed Articles