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Rotigotine for Apathy in Limbic Autoimmune Encephalitis
Carmela Gerace, M.D.; Fabio Massimo Corsi; Carlo Blundo
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:E42-E43. doi:10.1176/appi.neuropsych.12100259
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Dept. of Neurology
Azienda ospedaliera S.Camillo-Forlanini
Rome, Italy

Correspondence: c.gerace@tiscali.it

Copyright © 2013 by the American Psychiatric Association

Extract

To the Editor: A 58-year-old man was admitted to the Neurology department for subacute short-term memory loss and partial complex seizures. He was a retired teacher, and his past history was unremarkable. On admission, he was alert and quiet, partially disoriented in time; during observation, he often manifested temporary involvement of alertness, sometimes with involuntary movement of both arms. Neuropsychologic examination showed isolated involvement of memory function with absence of storage for verbal and spatial information.

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References

Starkstein  SE;  Mayberg  HS;  Preziosi  TJ  et al:  Reliability, validity, and clinical correlates of apathy in Parkinson’s disease.  J Neuropsychiatry Clin Neurosci 1992; 4:134–139
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Zuliani  L;  Graus  F;  Giometto  G  et al:  Central nervous system neuronal surface antibody-associated syndromes: review and guidelines for recognition.  J Neurol. Neurosurg Psychiatry 2012; 83:638, e645
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Graus  F;  Saiz  A;  Lai  M  et al:  Neuronal surface antigen antibodies in limbic encephalitis.  Neurology 2008; 71:930–936
[CrossRef] | [PubMed]
 
Levy  R;  Dubois  B:  Apathy and the functional anatomy of the prefrontal cortex–basal ganglia circuits.  Cerebral Cortex 2006; 16:916–928
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 Stahl’s Essential Psychopharmacology, 3rd Edition. New York,  Cambridge University Press, 2008, chap 19
 
Sanford  M;  Scott  LJ:  Rotigotine transdermal patch: a review of its use in the treatment of Parkinson’s disease.  CNS Drugs 2011; 25:699–719
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Rotigotine for apathy in limbic autoimmune encephalitis. J Neuropsychiatry Clin Neurosci 2013;25(4):E42-3.