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Orobuccolingual Dyskinesia After Long-Term Use of Black Cohosh and Ginseng
A. Sen, M.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:E50-E50. doi:10.1176/appi.neuropsych.12120395
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Financial Disclosure Statement: The author has not received any financial support for this clinical/scientific note.

Bakirkoy Research and Training Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey

Correspondence: e-mail: aysehir@yahoo.com

Copyright © 2013 by the American Psychiatric Association


To the Editor: Black cohosh (BC), also known as Cimicifuga racemosa, is a frequently used herbal remedy for alleviating menopausal symptoms.1 Ginseng has been widely used as herbal medicine in eastern Asia.2 We report a on a patient who developed orobuccolingual dyskinesia (OBLD) while being treated with an herbal supplement containing BC and ginseng.

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Wu  J;  Jeong  HK;  Bulin  SE  et al:  Ginsenosides protect striatal neurons in a cellular model of Huntington’s disease.  J Neurosci Res 2009; 87:1904–1912
[CrossRef] | [PubMed]
Huntley  A:  The safety of black cohosh (Actaea racemosa, Cimicifuga racemosa).  Expert Opin Drug Saf 2004; 3:615–623
[CrossRef] | [PubMed]
Lian  XY;  Zhang  Z;  Stringer  JL:  Protective effects of ginseng components in a rodent model of neurodegeneration.  Ann Neurol 2005; 57:642–648
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Vegeto  E;  Benedusi  V;  Maggi  A:  Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases.  Front Neuroendocrinol 2008; 29:507–519
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