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Neuropsychological Functioning in a Patient With Primary Angiitis of the CNS
Veronique Michiels, M.Psy., Ph.D.; Véronique Bissay, M.D.; Alex Michotte, M.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2014;26:E23. doi:10.1176/appi.neuropsych.13010008
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Dept. of Neurology

Dept. of Neurology
Dept. of Pathology (Neuropathology)
UZ Brussel, Vrije Universiteit Brussel (VUB)
Brussels, Belgium

Copyright © 2014 by the American Psychiatric Association


To the Editor: Primary angiitis of the central nervous system (PACNS), is a rare form of vasculitis restricted to the brain and spinal cord. The condition results in diffuse inflammation and destruction of small-to-medium sized blood vessels in the CNS. The clinical symptoms are nonspecific and reflect the diffuse nature of the pathological process. Headache is a common symptom. Other symptoms include cognitive impairment, stroke, transient ischemic attacks, cranial nerve involvement, myelopathy, seizures, and ataxia.1 Apart from reporting that cognitive deficits can be present, to-date no reports of cognitive and behavioral functioning in patients with PACNS have been published. Here, we describe the neuropsychological functioning of a patient with confirmed primary angiitis, at baseline and at 3 and 10 months of treatment with immunosuppressive medication.

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Hajj-Ali  RA;  Singhal  AB;  Benseler  S  et al:  Primary angiitis of the CNS.  Lancet Neurol 2011; 10:561–572
[CrossRef] | [PubMed]
Nasreddine  ZS;  Phillips  NA;  Bédirian  V  et al:  The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment.  J Am Geriatr Soc 2005; 53:695–699
[CrossRef] | [PubMed]
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