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Letters   |    
Ciprofloxacin-Induced Psychosis
Ashima Ranjan, M.B.B.S., D.P.M.; Samir Kumar Praharaj, M.B.B.S., M.D., D.P.M.
The Journal of Neuropsychiatry and Clinical Neurosciences 2014;26:E36-E37. doi:10.1176/appi.neuropsych.13020033
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Dept. of Psychiatry, Kasturba Medical College, Manipal, Karnataka, India

Correspondence: Dr. Praharaj; e-mail: samirpsyche@yahoo.co.in

Copyright © 2014 American Psychiatric Association

Extract

To the Editor: Ciprofloxacin is a broad-spectrum, bactericidal antibiotic of the fluoroquinolone group that is well-tolerated in adult population. Ciprofloxacin acts through binding two of the four topoisomerases of bacteria.1 Its common adverse effects include nausea, vomiting, diarrhea, abdominal discomfort, dizziness, headache, and rashes.2 Rarely, neuropsychiatric adverse effects such as psychosis occur with ciprofloxacin.3 We report on an acute psychosis that developed in a patient treated with ciprofloxacin for gastroenteritis and which resolved spontaneously after discontinuation.

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