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Letters   |    
The Effectiveness of High-Dosage Amisulpride Combined With Moderate-Dosage Sodium Valproate Treatment for an Overweight Patient With Psychotic Bipolar Disorder
Yi-Cheng Hou, M.Sc.; Chien-Han Lai, M.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2014;26:E34-E35. doi:10.1176/appi.neuropsych.13040091
View Author and Article Information

The authors report no financial relationships with commercial interests.

Department of Nutrition, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation New Taipei City, Taiwan, ROC

Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC

Send correspondence to Dr. Lai; e-mail: stephenlai99@gmail.com

Copyright © 2014 by the American Psychiatric Association

Extract

To the Editor: Several atypical antipsychotics were approved for the treatment of bipolar affective disorder.1 However, the data of amisulpiride in this field is still limited. I want to share a case of psychotic bipolar disorder with successful control of symptoms under the combined treatment of high-dosage amisulpiride and moderate-dosage sodium valproate.

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References

Derry  S;  Moore  RA:  Atypical antipsychotics in bipolar disorder: systematic review of randomised trials.  BMC Psychiatry 2007; 7:40
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Gentile  S:  Atypical antipsychotics for the treatment of bipolar disorder: more shadows than lights.  CNS Drugs 2007; 21:367–387
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Yatham  LN:  Acute and maintenance treatment of bipolar mania: the role of atypical antipsychotics.  Bipolar Disord 2003; 5(Suppl 2):7–19
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Yatham  LN:  Atypical antipsychotics for bipolar disorder.  Psychiatr Clin North Am 2005; 28:325–347
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Massat  I;  Souery  D;  Del-Favero  J  et al:  Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European Multicenter Association Study of affective disorders.  Am J Med Genet 2002; 114:177–185
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Chiaroni  P;  Azorin  JM;  Dassa  D  et al:  Possible involvement of the dopamine D3 receptor locus in subtypes of bipolar affective disorder.  Psychiatr Genet 2000; 10:43–49
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Chivers  JK;  Gommeren  W;  Leysen  JE  et al:  Comparison of the in-vitro receptor selectivity of substituted benzamide drugs for brain neurotransmitter receptors.  J Pharm Pharmacol 1988; 40:415–421
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