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Letters   |    
The Response of Psychotic Symptoms in a Patient With Resistant Schizophrenia Under Treatment of High-Dose Risperidone Long-Acting Injection
Yi-Cheng Hou, M.Sc.; Chien-Han Lai, M.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2014;26:E16-E17. doi:10.1176/appi.neuropsych.13070150
View Author and Article Information

The authors report no financial relationships with commercial interests.

Dept. of Nutrition, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan, ROC

Dept. of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan, ROC
Dept. of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC

Send correspondence to Dr. Lai; e-mail: stephenlai99@gmail.com

Copyright © 2014 by the American Psychiatric Association

Extract

To the Editor: Treatment-resistant schizophrenia is very difficult to treat because of the refractory characteristics toward the antipsychotic treatment. It seems not properly controlled by monotherapy of an antipsychotic. We present a case of treatment-resistant schizophrenia in a patient who experienced better control of psychotic symptoms after high-dose long-acting injection of risperidone.

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References

Meltzer  HY:  Treatment-resistant schizophrenia—the role of clozapine.  Curr Med Res Opin 1997; 14:1–20
[CrossRef] | [PubMed]
 
Peuskens  J;  Olivares  JM;  Pecenak  J  et al:  Treatment retention with risperidone long-acting injection: 24-month results from the Electronic Schizophrenia Treatment Adherence Registry (e-STAR) in six countries.  Curr Med Res Opin 2010; 26:501–509
[CrossRef] | [PubMed]
 
Ikai  S;  Remington  G;  Suzuki  T  et al:  A cross-sectional study of plasma risperidone levels with risperidone long-acting injectable: implications for dopamine D2 receptor occupancy during maintenance treatment in schizophrenia.  J Clin Psychiatry 2012; 73:1147–1152
[CrossRef] | [PubMed]
 
Wheeler  A;  Vanderpyl  J;  Carswell  C  et al:  Explicit review of risperidone long-acting injection prescribing practice.  J Clin Pharm Ther 2011; 36:651–663
[CrossRef] | [PubMed]
 
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