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Letters   |    
Obsessive-Compulsive Symptoms in Schizophrenia: Treatment Challenges
Nabil Kotbi, M.D.; Matthew Goodwin, M.D., Ph.D.; Dimitry Francois, M.D.; Smita Agarkar, M.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2014;26:E31-E33. doi:10.1176/appi.neuropsych.13070166
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Weill Cornell Medical College, New York.

Send correspondence to Smita Agarkar, M.D.; e-mail: smd9004@med.cornell.edu

Copyright © 2014 by the American Psychiatric Association


Obsessive-compulsive symptoms (OCS) are highly prevalent in schizophrenia, estimated to be present in 14% of schizophrenic patients.1 Optimal treatment options for those patients are yet to be agreed upon, perhaps because mechanisms underlying the interface between both diseases are poorly understood.2 Recent studies have focused on distinguishing the order of development of schizophrenia and obsessive-compulsive disorder in patients with both conditions in an effort to elucidate a response to treatment.3 It has been suggested that OCS leads to severe impairment in functioning that might diminish the quality of life. Here we report two cases: both patients had obsessive-compulsive symptoms, however, they developed at different stages of the illness. Using these cases we present a brief literature review of the treatment challenge of obsessive-compulsive symptoms in schizophrenia.

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