Odor discrimination deficits were found in 80% of 20 schizophrenia
patients and in none of the 20 age- and sex-matched comparison subjects.
Olfactory discrimination was reliably measured in the patients. Twelve
patients in this study also had smooth pursuit eye movement (SPEM)
qualitatively recorded. The olfactory discrimination scores were highly
correlated to SPEM but not to other clinical measures. This correlation
suggests a shared neurobiology, possibly involving working memory.