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Clinical and Research Reports   |    
Comparison of the Profile of Patients With Acute and Transient Psychotic Disorder and Schizophrenia in a Nigerian Teaching Hospital
Oluyomi Esan, MBBS, M.Sc., FWACP; Olufunmilayo Fawole, MBBS, M.Sc., FMCPH, FWACP
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:327-334. doi:10.1176/appi.neuropsych.12120397
View Author and Article Information

From the Dept. of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Nigeria.

Send correspondence to Dr. Oluyomi Babafemi Esan; e-mail: oluyomie@yahoo.com

Copyright © 2013 by the American Psychiatric Association

Received December 12, 2012; Revised March 01, 2013; Revised March 25, 2013; Accepted March 26, 2013.

Abstract

Acute and transient psychotic disorders (ATPD) are different from schizophrenia; however, very little research has been done on this disorder in low-income countries, where the incidence is as high as 10 times the incidence in the more developed countries. The authors sought to identify/characterize the sociodemographic and clinical differences between the two disorders by performing a retrospective review of the records of patients with untreated first episode of ATPD and schizophrenia seen at the University College Hospital, Ibadan, between January 1, 2006 and December 31, 2010, extracting sociodemographic and clinical data. A group of 243 patients with schizophrenia and 124 subjects with ATPD met the inclusion criteria. Patients with ATPD were more likely to present below the age of 25 years. Excitement was more common in ATPD than in schizophrenia; suspiciousness was more common in subjects with schizophrenia than ATPD. Also, anxiety and uncooperativeness were significantly more likely to occur in ATPD. Poor orientation, disturbance of volition, and preoccupation were more common in schizophrenia. The mean age at onset was similar between patients with schizophrenia and ATPD. In keeping with findings in Europe and North America, there are clinical and sociodemographic differences between ATPD and schizophrenia; however, a different set of features differentiate between the two conditions in Nigerians.

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TABLE 1.Comparison of the Sociodemographic Characteristics of Subjects With Untreated First Episode of Acute and Transient Psychotic Disorder (ATPD) and Schizophrenia Seen at the University College Hospital, Ibadan, between January 2006 and December 2010
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TABLE 2.Comparison of Means Between Subjects With Untreated First Episode of ATPD and First Episode of Schizophrenia Seen at the University College Hospital, Ibadan, Between January 2006 and December 2010
Table Footer Note

SD: standard deviation.

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TABLE 3.Comparison of General and Psychotic Symptoms Between Subjects With Untreated First Episode of ATPD and Schizophrenia Seen at the University College Hospital, Ibadan, Between January 2006 and December 2010
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TABLE 4.Factors Predictive of Schizophrenia by Logistic Regression
Table Footer Note

a Reference measure.

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TABLE 5.Factors Predictive of Acute and Transient Psychotic Disorder (ATPD) by Logistic Regression
Table Footer Note

a Reference measure.

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