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Letters   |    
“Lexical Alexia” in a Chinese Semantic Dementia Patient
Simon Kang Seng Ting, M.D.; Shahul Hameed, M.D.
The Journal of Neuropsychiatry and Clinical Neurosciences 2013;25:E37-E38. doi:10.1176/appi.neuropsych.12100247
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Dept. of Neurology, National Neuroscience Institute
Singapore General Hospital

Correspondence: Dr. Ting; e-mail: simon.ting.k.s@sgh.com.sg

Copyright © 2013 by the American Psychiatric Association


To the Editor: Semantic dementia (SD) is characterized by impaired ability in understanding the meaning of words, anomia, and surface dyslexia, but spared speech production.1 Neuroimaging typically shows anterior temporal lobe atrophy and hypometabolism in functional imaging.2,3 New diagnostic criteria have been proposed by Gorno-Tempini ML et al. in 2011, which incorporated the clinical and radiological characteristics of SD.4

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FIGURE 1. MRI T1 (left) and FLAIR (right) Images Showing Bilateral Anterior Temporal Atrophy, Right > Left


Hodges  JR;  Patterson  K;  Oxbury  S  et al:  Semantic dementia. Progressive fluent aphasia with temporal lobe atrophy.  Brain 1992; 115:1783–1806
[CrossRef] | [PubMed]
Rosen  HJ;  Gorno-Tempini  ML;  Goldman  WP  et al:  Patterns of brain atrophy in frontotemporal dementia and semantic dementia.  Neurology 2002; 58:198–208
[CrossRef] | [PubMed]
Foster  NL;  Heidebrink  JL;  Clark  CM  et al:  FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer’s disease.  Brain 2007; 130:2616–2635
[CrossRef] | [PubMed]
Gorno-Tempini  ML;  Hillis  AE;  Weintraub  S  et al:  Classification of primary progressive aphasia and its variants.  Neurology 2011; 76:1006–1014
[CrossRef] | [PubMed]
Wilson  SM;  Brambati  SM;  Henry  RG  et al:  The neural basis of surface dyslexia in semantic dementia.  Brain 2009; 132:71–86
[CrossRef] | [PubMed]
Chinese State Language Work Committee:  Basic vocabulary table of modern Chinese characters .  Beijing,  Language and Literature Press, 1988
Evans  JJ;  Heggs  AJ;  Antoun  N  et al:  Progressive prosopagnosia associated with selective right temporal lobe atrophy. A new syndrome? Brain 1995; 118:1–13
[CrossRef] | [PubMed]
Mummery  CJ;  Patterson  K;  Wise  RJ  et al:  Disrupted temporal lobe connections in semantic dementia.  Brain 1999; 122:61–73
[CrossRef] | [PubMed]
Weeks  B;  Chen  HQ:  Surface Dyslexia in Chinese.  Neurocase 1999; 5:161–172
Zhang  YM;  Huang  Y;  Sun  XJ  et al:  Clinical and imaging features of a Chinese-speaking man with semantic dementia.  J Neurol 2008; 255:297–298
[CrossRef] | [PubMed]
Luo  BY;  Zhao  XY;  Wang  YW  et al:  Is surface dyslexia in Chinese the same as in alphabetic one? Chin Med J (Engl) 2007; 120:348–349
Zhang  Q;  Damian  MF:  Effects of orthography on speech production in Chinese.  J Psycholinguist Res 2012; 41:267–283
[CrossRef] | [PubMed]
Kong  L;  Zhang  JX;  Ho  CS  et al:  Phonology and access to Chinese character meaning.  Psychol Rep 2010; 107:899–913
[CrossRef] | [PubMed]
Tan  LH;  Laird  AR;  Li  K  et al:  Neuroanatomical correlates of phonological processing of Chinese characters and alphabetic words: a meta-analysis.  Hum Brain Mapp 2005; 25:83–91
[CrossRef] | [PubMed]
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