In this pilot study, a prolonged (interictal) delirium was induced by
electroconvulsive therapy (ECT) in seven out of seven depressed patients
with Parkinson's disease. This occurrence of delirium appears much higher
than what has been reported in other patient populations. These findings
are consistent with several lines of data that have implicated the basal
ganglia in the development of delirium from other causes, and they suggest
that structural changes in these areas may predispose individuals to
develop an interictal delirium during a course of ECT.