The effects of buspirone and verapamil on spasmodic torticollis were
investigated in two double-blind, placebo-controlled crossover studies.
Buspirone was given in doses of 20-100 mg/day for 4 weeks to 14 patients;
verapamil was given in doses of 40-100 mg/day for 3 weeks to 8 patients.
Neither drug improved symptoms of the movement disorder (posture, motility,
rigidity, tremor), pain, perceived stress, or mood, either in the whole
group or in any individual patient.