BRAINBLAST, a program that uses voxel processing, was developed in order
to produce high-fidelity three-dimensional reconstructions of the brain.
Four steps were used to produce images: washing away cerebrospinal fluid
(via histogramming), dissecting away the blood vessels (via a connectivity
heuristic), highlighting the sulci and gyri (via a lighting model), and
resampling the interior contents of the brain. After reconstruction, the
images can be resampled, rotated, written on, measured, or redissected. The
technique has a variety of applications: study of individual variation in
sulcal and gyral patterns, evaluation of structure/function relationships,
measurement of volumes or subregions using anatomically defined landmarks,
and teaching of neuroanatomy.