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The Journal of Neuropsychiatry and Clinical Neurosciences, VOL. 5, No. 3

Article | August 01, 1993

Cerebrospinal fluid thyrotropin-releasing hormone concentrations in patients with anxiety disorders

The Journal of Neuropsychiatry and Clinical Neurosciences 1993;5:335-337.

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Abstract

In a study of 45 patients with anxiety disorders and 11 control subjects, mean cerebrospinal fluid (CSF) concentrations of thyrotropin- releasing hormone (TRH) were not significantly different between nonpsychiatric control subjects and those with panic disorder, generalized anxiety disorder, or obsessive-compulsive disorder. Male subjects, regardless of diagnosis, had significantly higher mean CSF concentrations of TRH than females.

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