The authors review 1) the pathophysiological, neuroimaging, and
neurobehavioral evidence for frontal lobe involvement in closed head
injury; 2) studies elucidating the cognitive deficits and behavioral
disturbance related to frontal lobe lesions associated with head injury;
and 3) pharmacologic treatment of the neuropsychiatric manifestations of
frontal lobe injury, including emerging therapies.
Abstract Teaser