Male Alzheimer's disease patients, studied with 18-fluoro-2-
deoxyglucose positron emission tomography while performing a verbal memory
test, showed a right-greater-than-left asymmetry of cortical metabolism
that tended to be greater than that in healthy, age-matched control
subjects. This asymmetry was absent in female patients, preliminarily
suggesting a propensity for left hemispheric involvement in the Alzheimer's
disease process in males.