Prevalence of Alzheimer's Disease and Apolipoprotein E Allele Frequencies in the Old Order Amish



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	Geriatric Psychiatry
	Alzheimer's Disease

J Neuropsychiatry Clin Neurosci 10:100-102, February 1998
© 1998 American Psychiatric Press, Inc.

Clinical and Research Report

Prevalence of Alzheimer's Disease and Apolipoprotein E Allele Frequencies in the Old Order Amish

Jimmy Holder, B.A. and Andrew C. Warren, M.B., B.S., D.Phil.

Received August 26, 1996; revised January 9, 1997; accepted January 13, 1997. From the Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205. Send correspondence to Dr. Warren at the above address.

The authors examined the prevalence of Alzheimer's disease andapolipoprotein E allele frequencies in the Old Order Amish.A lower frequency of dementia in the Amish does not appear tobe due to a reduced E4 frequency.

Key Words: Alzheimer's Disease; Apolipoprotein E; Amish

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