J Neuropsychiatry Clin Neurosci 10:34-40, February 1998
© 1998 American Psychiatric Press, Inc.
Effect of Anxiety Disorder on Impairment and Recovery From Stroke
Kengo Shimoda, M.D. and
Robert G. Robinson, M.D.
Received March 6, 1996; revised August 20, 1996; accepted September 26, 1996. From the Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa; and Department of Neuropsychiatry, Nippon Medical School, Tokyo, Japan. Address correspondence to Dr. Robinson, Department of Psychiatry, University of Iowa Hospitals and Clinics, 200 Hawkins Drive #2887 JPP, Iowa City, IA 52242-1057.
The effect of anxiety disorder on recovery from impairment following stroke was examined in 142 patients with acute stroke who had follow-up evaluations. Anxiety disorder significantly interacted with depression to influence the severity and course of depression, outcome of activities of daily living, and social functioning. Anxiety disorder, however, did not affect cognitive impairment, which was influenced only by major depression. These data suggest that the existence of anxiety disorders plays an important role in the prognosis of patients with poststroke depression. These data also suggest that depression and anxiety disorder may have different mechanisms.
Key Words: Stroke; Anxiety Disorder; Depression and Anxiety, Comorbid
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