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Risperidone for the Treatment of Behavioral Disturbances in Dementia

A Case Series

Received January 13, 1997; revised March 24, 1997; accepted April 9, 1997. From Sunnybrook Health Science Centre, University of Toronto; Royal Ottawa Hospital, University of Ottawa; The Nova Scotia Hospital, Dalhousie University, Halifax, Nova Scotia; London Psychiatric Hospital, London, Ontario; and St. Boniface General Hospital, Winnipeg, Manitoba, Canada. Address correspondence to Dr. Herrmann, Division of Geriatric Psychiatry, Sunnybrook Health Science Centre, 2075 Bayview Avenue, Room FG20, North York, ON M4N 3M5, Canada; e-mail: n.herrmann{at}utoronto.ca

The authors describe a series of 22 patients with dementia and behavioral disturbances, including agitation, aggression, delusions, and hallucinations, who were treated with risperidone. Risperidone, in low doses, was well tolerated; 50% of patients experienced significant improvement, although 50% experienced some extrapyramidal symptoms.

Key Words: Risperidone • Behavioral Disturbance • Dementia

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