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J Neuropsychiatry Clin Neurosci 10:354-358, August 1998
© 1998 American Psychiatric Press, Inc.


Clinical and Research Report

Klüver-Bucy Syndrome After Bilateral Selective Damage of Amygdala and Its Cortical Connections

L. Anne Hayman, M.D., Jennie L. Rexer, M.A., Marykay A. Pavol, Ph.D., Daniel Strite, M.A. and Christina A. Meyers, Ph.D.

Received May 27, 1997; revised August 11, 1997; accepted August 14, 1997. From the Department of Radiology, Baylor College of Medicine, and Department of Neuro-Oncology, M.D. Anderson Cancer Center, Houston, Texas. Address correspondence to Dr. Meyers, Department of Neuro-Oncology, Box 100, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030.

Isolated symmetric damage to the amygdalae and their cortical connections occurred in an individual following cancer treatment. The lesions were imaged after reversal of hyponatremia. The patient displayed marked behavioral changes including visual agnosia, hypersexuality, hyperorality, a tendency to react to every visual stimulus, and memory deficits. The cluster of neurobehavioral symptoms is similar to previously reported accounts of Klüver-Bucy syndrome and suggests the importance of bilateral amygdala involvement in these behavioral changes.

Key Words: Amygdala • Limbic System • Klüver-Bucy Syndrome




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J. Neuropsychiatry Clin. Neurosi.Home page
B. T. Carroll, H. W. Goforth, and L. A. Carroll
Anatomic Basis of Kluver-Bucy Syndrome
J Neuropsychiatry Clin Neurosci, February 1, 1999; 11(1): 116 - 116.
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