J Neuropsychiatry Clin Neurosci 11:190-208, May 1999
© 1999 American Psychiatric Press, Inc.
Conventional and Quantitative Electroencephalography in Psychiatry
John R. Hughes, M.D., Ph.D. and
E. Roy John, Ph.D.
Received April 9, 1998; revised accepted May 22, 1998. From the Department of Neurology, University of Illinois School of Medicine, Chicago, Illinois; Department of Psychiatry, New York University Medical Center, New York, New York; and Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York. Address correspondence to Dr. John, Brain Research Laboratories, New York University Medical Center, 550 First Avenue, New York, NY, 10016.
Electrical activity of each brain region is homeostatically regulated, resulting in predictable frequency composition of the background EEG. Replicated normative databases have established that the EEG power spectrum is independent of ethnic background. Artifact-free EEG evaluated relative to such norms displays few deviant values in healthy, normally functioning individuals. In subjects with psychiatric disorders, high proportions of abnormal findings have been reported with good concordance and high specificity and sensitivity across numerous studies, distinctive within a wide variety of disorders and often contributing to differential diagnosis and selection of treatment. New three-dimensional QEEG imaging methods offer an economical alternative to other functional brain imaging modalities.
Key Words: Electroencephalography
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