J Neuropsychiatry Clin Neurosci 12:233-239, May 2000
© 2000 American Psychiatric Press, Inc.
Validation of the NPI-Q, a Brief Clinical Form of the Neuropsychiatric Inventory
Daniel I. Kaufer, M.D.,
Jeffrey L. Cummings, M.D.,
Patrick Ketchel, M.Ed.,
Vanessa Smith,
Audrey MacMillan, C.R.N.P.,
Timothy Shelley, M.S.W.,
Oscar L. Lopez, M.D. and
Steven T. DeKosky, M.D.
Received January 19, 1999; revised August 9, 1999; accepted October 1, 1999. From the Departments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, and Departments of Neurology and Psychiatry & Biobehavioral Sciences, University of California at Los Angeles. Address correspondence to Dr. Kaufer, 4 West, UPMC Montefiore, 200 Lothrop Street, Pittsburgh, PA 15213; e-mail: dkaufer{at}vms.cis.pitt.edu
The Neuropsychiatric Inventory (NPI) is a validated clinical instrument for evaluating psychopathology in dementia. The authors developed a brief questionnaire form of the NPI (NPI-Q), intended for use in routine clinical practice, and cross-validated it with the NPI in 60 Alzheimer's patients. Test-retest reliability of the NPI-Q was acceptable. The prevalence of analogous symptoms reported on the NPI and NPI-Q differed on average by 5%; moderate or severe symptom ratings differed by less than 2%. The NPI-Q provides a brief, reliable, informant-based assessment of neuropsychiatric symptoms and associated caregiver distress that may be suitable for use in general clinical practice.
Key Words: Alzheimer's Disease • Dementia • Agitation
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