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* Amphetamines
J Neuropsychiatry Clin Neurosci 12:480-484, November 2000
© 2000 American Psychiatric Press, Inc.

Psychiatric Comorbidity of Methamphetamine Dependence in a Forensic Sample

Ari D. Kalechstein, Ph.D., Thomas F. Newton, M.D., Douglas Longshore, Ph.D., M. Douglas Anglin, Ph.D., Wilfred G. van Gorp, Ph.D. and Frank H. Gawin, M.D.

Received November 15, 1999; revised December 7, 1999; accepted January 13, 2000. From the Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, California; Veterans Affairs Medical Center, West Los Angeles, California; Department of Psychiatry, Cornell University School of Medicine, New York, New York; Center for the Study of Addictions, UCLA School of Medicine; and Mood and Addiction Neuroscience Foundation, Los Angeles, California. Address correspondence to Dr. Kalechstein, UCLA Neuropsychiatric Institute, 760 Westwood Plaza, Room A7-372, Los Angeles, CA 90024; e-mail: adk{at}ucla.edu

The objective of this study was to examine the association between psychiatric symptoms and methamphetamine dependence. A four-hour survey was administered to 1,580 arrestees sampled from the 14 most populous counties in California. The survey included items assessing demographic profile, history of substance dependence, and psychiatric symptomatology. In the 12 months prior to the assessment, methamphetamine-dependent individuals were more likely to report depressive symptoms and suicidal ideation than individuals denying methamphetamine dependence, even after controlling for demographic profile and dependence on other drugs. Methamphetamine-dependent individuals also were more likely to report a need for psychiatric assistance at the time of the interview. These findings suggest that methamphetamine-dependent individuals are at greater risk to experience particular psychiatric symptoms. Further study to determine the etiology of these symptoms is warranted.

Key Words: Amphetamines • Forensic Psychiatry • Substance Abuse • Suicide and Suicidality




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