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Clinical Features Characterizing Young-Onset and Intermediate-Onset Schizophrenia

Received August 18, 1999; revised December 8, 1999; accepted December 22, 1999. From the University of Iowa, Department of Psychiatry, Mental Health Clinical Research Center, University of Iowa, Iowa City. Address correspondence to Dr. Schultz, Department of Psychiatry, University of Iowa College of Medicine, Psychiatry Research, 1-189A MEB, Iowa City, IA 52242; e-mail: susan-schultz{at}uiowa.edu

ABSTRACT

Late-onset schizophrenia has been noted to have distinct clinical characteristics. The authors compared symptom characteristics between early- and intermediate-onset patients (N=259) to determine whether clinical features distinguished differences within younger populations. On global measures of psychotic, disorganized, and negative symptoms, early-onset patients had greater disorganized and negative symptoms but did not differ in hallucinations and delusions. The dichotomy of early vs. late onset may extend to a younger population, reflecting a more continuous influence.

Key Words: Schizophrenia Spectrum Disorder • Age of Onset

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