J Neuropsychiatry Clin Neurosci 13:229-242, May 2001
© 2001 American Psychiatric Press, Inc.
Validation of the Delirium Rating Scale-Revised-98
Comparison With the Delirium Rating Scale and the Cognitive Test for Delirium
Paula T. Trzepacz, M.D.,
Dinesh Mittal, M.D.,
Rafael Torres, M.D.,
Kim Kanary, B.S.,
John Norton, M.D. and
Nita Jimerson, M.S.N.
Received February 22, 2000; accepted July 21, 2000. From the University of Mississippi Medical Center and the Sonny Montgomery Veterans Affairs Medical Center, Jackson, Mississippi; and the Eli Lilly and Company, Neuroscience Research, U.S. Affiliate, Indianapolis, Indiana. Address correspondence to Dr. Trzepacz, Lilly Corporate Center, drop code 4133, Indianapolis, IN 46285. E-mail: PTT{at}lilly.com
The DRS-R-98, a 16-item clinician-rated scale with 13 severity items and 3 diagnostic items, was validated against the Cognitive Test for Delirium (CTD), Clinical Global Impression scale (CGI), and Delirium Rating Scale (DRS) among five diagnostic groups (N=68): delirium, dementia, depression, schizophrenia, and other. Mean and median DRS-R-98 scores significantly (P<0.001) distinguished delirium from each other group. DRS-R-98 total scores correlated highly with DRS, CTD, and CGI scores. Interrater reliability and internal consistency were very high. Cutoff scores for delirium are recommended based on ROC analyses (sensitivity and specificity ranges: total, 91%–100% and 85%–100%; severity, 86%–100% and 77%–93%, respectively, depending on the cutoffs or comparison groups chosen). The DRS-R-98 is a valid measure of delirium severity over a broad range of symptoms and is a useful diagnostic and assessment tool. The DRS-R-98 is ideal for longitudinal studies.
Key Words: Delirium • Rating Instruments
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