
J Neuropsychiatry Clin Neurosci 13:258-260, May 2001
© 2001 American Psychiatric Press, Inc.
Clinical and Research Reports |
Dentatorubral-Pallidoluysian Atrophy (DRPLA) Presenting With Psychosis
Naoto Adachi, M.D.,
Kunimasa Arima, M.D.,
Takashi Asada, M.D.,
Masaaki Kato, M.D.,
Narihiro Minami, M.D.,
Yu-ichi Goto, M.D.,
Teiichi Onuma, M.D.,
Takeshi Ikeuchi, M.D.,
Shoji Tsuji, M.D.,
Masahiro Hayashi, M.D. and
Yuken Fukutani, M.D.
Received April 7, 2000; revised August 16, 2000; accepted September 7, 2000. From the National Center of Neurology and Psychiatry, Kodaira, Japan; Adachi Mental Clinic, Sapporo; Tokyo Institute of Psychiatry, Tokyo; Department of Neurology, Brain Research Institute, Niigata University, Niigata; National Hokuriku Hospital, Joana; and Department of Neuropsychiatry, Fukui Medical University, Fukui, Japan. Address correspondence to Dr. Adachi, Adachi Mental Clinic, Kitano 7-5-12-40, Kiyota, Sapporo 004-0867, Japan. E-mail: adacchan{at}tky2.3web.ne.jp
ABSTRACT
The authors report on four DRPLA patients who manifested delusions. All patients demonstrated autosomal dominant DRPLA confirmed by standard gene analysis. Patients with DRPLA can exhibit a variety of psychiatric symptoms in addition to extrapyramidal and cerebellar symptoms.
Key Words: Dentatorubral-Pallidoluysian Atrophy (DRPLA) Psychosis Gene Analysis
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