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Relationship of Gender and Age at Onset of Schizophrenia to Severity of Dyskinesia

Received June 7, 2000; revised October 16, 2000; accepted November 16, 2000. From the Department of Psychiatry, University of California–San Diego, and the Psychiatry and Psychology Services, VA San Diego Healthcare System, San Diego, California. Address correspondence to Dr. Lindamer, VA San Diego Healthcare Systems, 116A, 3350 La Jolla Village Drive, San Diego, CA 92161. E-mail: llindamer{at}ucsd.edu

ABSTRACT

The authors examined severity of dyskinesia in 119 men and 44 women, comparing by gender those with late-onset schizophrenia (LOS) versus early-onset schizophrenia (EOS). Women with LOS and men with EOS had more severe dyskinesia than men with LOS and women with EOS. Many factors, including the length of neuroleptic treatment, alcohol and smoking history, and menopausal status, may contribute to the severity of dyskinesia in older patients with schizophrenia.

Key Words: Schizophrenia • Dyskinesia

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