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Apolipoprotein E Gender Effects on Cognitive Performance in Age-Associated Memory Impairment

Received May 31, 2000; revised February 1, 2000; accepted February 5, 2001. From the Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Catalunya, Spain. Address correspondence to Dr. Bartrés-Faz, Department of Psychiatry and Clinical Psychobiology, Faculty of Medicine, University of Barcelona, IDiBAPS asamova 143, 08036, Barcelona, Spain. E-mail: dbartres{at}psi.ub.es

ABSTRACT

Among 100 individuals with age-associated memory impairment (AAMI), APOE E4 carriers performed worse on memory. However, when subjects were considered by gender, this effect was only observed in females. APOE E4 may have a more robust cognitive influence on female than on male individuals with AAMI.

Key Words: Genes • Memory • Geriatric Neuropsychiatry

This article has been cited by other articles:

				E. E. Sundermann, P. E. Gilbert, and C. Murphy Apolipoprotein E {varepsilon}4 Genotype and Gender: Effects on Memory Am J Geriatr Psychiatry, October 1, 2007; 15(10): 869 - 878. [Abstract] [Full Text] [PDF]

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