Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via HighWire Citing Articles via Google Scholar Articles by Hofman, P. A.M. Articles by Jolles, J. Search for Related Content PubMed Citation Articles by Hofman, P. A.M. Articles by Jolles, J. Neurophysiology

Brain Lesions in Patients Visiting a Memory Clinic With Postconcussional Sequelae After Mild to Moderate Brain Injury

Received March 2, 2000; revised January 3, 2001; accepted January 10, 2001. From the Department of Radiology (P.A.M.H., J.T.W.) and Department of Psychiatry and Neuropsychology (F.R.J.V., J.J., N.R.), University Hospital Maastricht, The Netherlands. Address correspondence to Dr. Hofman, Department of Radiology, University Hospital Maastricht, P.O. Box 5800 6200 AZ Maastricht. E-mail: pho{at}rdia.azm.nl

Postconcussional disorder after a relatively mild head injury is common. Although a partial organic etiology is presumed, little imaging evidence exists for this assumption. In this study, patients with mild to moderate brain injury (median Glasgow Coma Scale score of 14) had more parenchymal brain lesions than control subjects (P=0.02). Additionally, the authors investigated the potential of quantifying brain injury by the magnetization transfer ratio (MTR). The curve amplitude of the MTR histogram was used as a measure of normal white matter. Patients had a lower curve amplitude than control subjects (P=0.008). This study provides evidence of persistent traumatic brain alterations in patients who sustained a relatively mild traumatic brain injury.

Key Words: Neuropsychology • Postconcussional Disorder • Traumatic Brain Injury

This article has been cited by other articles:

				W. L. Maxwell, M.-A. MacKinnon, J. E. Stewart, and D. I. Graham Stereology of cerebral cortex after traumatic brain injury matched to the Glasgow Outcome Score Brain, November 6, 2009; (2009) awp264v1. [Abstract] [Full Text] [PDF]

				M. H. Heitger, R. D. Jones, A. D. Macleod, D. L. Snell, C. M. Frampton, and T. J. Anderson Impaired eye movements in post-concussion syndrome indicate suboptimal brain function beyond the influence of depression, malingering or intellectual ability Brain, October 1, 2009; 132(10): 2850 - 2870. [Abstract] [Full Text] [PDF]

				J. Carr Postconcussion syndrome: a review Trauma, January 1, 2007; 9(1): 21 - 27. [Abstract] [PDF]

				T. Anderson, M. Heitger, and A D Macleod Concussion and mild head injury Practical Neurology, December 1, 2006; 6(6): 342 - 357. [Full Text] [PDF]

				C. I. Halterman, J. Langan, A. Drew, E. Rodriguez, L. R. Osternig, L.-S. Chou, and P. v. Donkelaar Tracking the recovery of visuospatial attention deficits in mild traumatic brain injury Brain, March 1, 2006; 129(3): 747 - 753. [Abstract] [Full Text] [PDF]

				M. H. Heitger, T. J. Anderson, R. D. Jones, J. C. Dalrymple-Alford, C. M. Frampton, and M. W. Ardagh Eye movement and visuomotor arm movement deficits following mild closed head injury Brain, March 1, 2004; 127(3): 575 - 590. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 2002 American Neuropsychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us