J Neuropsychiatry Clin Neurosci 14:210-213, May 2002
© 2002 American Psychiatric Press, Inc.
Clinical and Research Reports |
Interictal Schizophrenia-like Psychosis in a Patient With Double Cortex Syndrome
Nozomi Akanuma, M.D.,
Osamu Saitoh, M.D.,
Takeo Yoshikawa, M.D.,
Hiroshi Matsuda, M.D.,
Nako Ishikura, M.D.,
Masaaki Kato, M.D.,
Naoto Adachi, M.D. and
Teiichi Onuma, M.D.
Received December 22, 2000; revised April 5, 2001; accepted April 11, 2001. From the Department of Neuropsychiatry, Faculty of Medicine, Tokyo Medical and Dental University, Tokyo; National Center Hospital for Mental, Nervous and Muscular Disorders, NCNP, Kodaira; and Laboratory for Molecular Psychiatry, Brain Science Institute, Riken, Wako, Japan. Address correspondence to Dr. Akanuma, Department of Clinical Neurophysiology, King's College Hospital, Denmark Hill, London SE5 9RS, UK. E-mail: n_akanuma{at}hotmail.com
ABSTRACT
The authors report a female patient with sporadic double cortex syndrome who manifested recurrent interictal schizophrenia-like psychoses. She had no mutations in the doublecortin gene but a pericentric inversion of chromosome 9. Neurodevelopmental disturbances and seizures may be associated with her mental dysfunction.
Key Words: Epilepsy • Psychosis • Double Cortex Syndrome
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