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Effectiveness of Switching to Quetiapine for Neuroleptic-Induced Amenorrhea

Received March 6, 2002; revised June 12, 2002; accepted June 20, 2002. From the Department of Neuropsychiatry, Akita University School of Medicine, Hondo, Akita City, Japan; Yokote Kohsei Hospital, Japan. Address correspondence to Dr. Hitoshi Takahashi, Department of Neuropsychiatry, Akita University School of Medicine, 1-1-1 Hondo, Akita-City, 010-8543, Japan; hito_takahashi{at}hotmail.com (E-mail).

ABSTRACT

This study investigated the effectiveness and tolerability of a switching strategy using quetiapine in 16 women with schizophrenia who were suffering from haloperidol- or risperidone-induced amenorrhea. Findings revealed that 10 patients (71.6%) resumed menstruation, without worsening of psychotic symptoms.

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